(Professora Auxiliar)
    Telf.: 300 001 705 | E-Mail:

    Unidade(s) Curricular(es):

    Curriculum Vitae Resumido:

      Catarina S. Nunes is an Assistant Professor at Universidade Aberta since January 2014. She has been in academia since 2003, lecturing disciplines in areas ranging from Biostatistics; Probability and Statistics; Applied Statistics; Stochastic Processes; Control Systems; Financial Mathematics; Signal Processing; Optimization; Intelligent Systems; Statistical and Mathematical Modelling.

      Catarina S Nunes already supervised than 4 PhD students (in Biomedical Sciences, Biomedical Engineering and Mechanical Engineering), more than 15 MSc students (in Statistics; Engineering with Finance; Engineering with Business Management; Automation; Statistics, Mathematics and Computation; Biostatistics and Biometry), and many undergraduate final year projects. Since 2005, she has been part of 4 research projects, two of which as leading researcher, one clinical trial and several observational clinical studies. At the moment, Catarina S Nunes supervises or co-supervises 10 PhD students in different areas such as Applied Mathematics and Modelling, Medical Sciences and Biomedical Engineering.


      Coordenadora da Secção de Matemática (Novembro 2018 - …)

      Coordenadora do Mestrado de Estatística, Matemática e Computação (2016 - ....).

      Vice-coordenadora do Mestrado de Estatística, Matemática e Computação (2014 - 2016).

    Habilitações Académicas:

      ·         Post-graduate Certificate in Academic Practice, King’s Learning Institute, King’s College London, 2011 

      ·         Ph.D. – Doctor of Phylosophy, University of Sheffield, United Kingdom, 2003

      ·         Research Training Programme, University of Sheffield, United Kingdom, 1999

      ·         Licenciatura (4-years undergraduate course, similar to MSci) in Applied Mathematics to Technology, Faculty of Sciences of the University of Porto, Portugal, 1998

    Experiência Profissional:

      ·         Assistant Professor, 2014 - ----
      Department of Sciences and Technology, Universidade Aberta, Delegação do Porto, Portugal

      ·         Assistant Researcher, 2013

      Catedra of Pain Medicine, Department of Experimental Biology, Faculty of Medicine of the University of Porto, Portugal

      ·         Research Consultant since 2012

      Serviço de Anestesiologia, Centro Hospitalar do Porto, Porto, Portugal

      ·         Lecturer,  2007 – 2011
      Permanent contract – Division of Engineering, School of Natural & Mathematical Sciences, King´s College London, United Kingdom

      ·         Invited Assistant Professor, 2003 - 2007
      Department of Applied Mathematics, Faculty of Sciences of the University of Porto, Portugal

      ·         Post-Doc Researcher, 2004 - 2007
       Department of Applied Mathematics, Faculty of Sciences of the University of Porto, Portugal & Department of Anaesthesiology, Hospital Geral of Santo António, Porto, Portugal


    Área(s) de Interesse Científico e de Investigação:

      ·         Biostatistics (population studies, drug effects, drug impact);

      ·         Mathematical modelling (pharmacokinetic and dynamic drug models, physiological models, population models);

      ·         Clinical response analysis and identification;

      ·         Optimization and data analysis;

      ·         Statistical and Digital Signal Processing (EEG, ECG, EMG, Arterial pressure, evoked potentials);

      ·         Intelligent Systems for data modelling (Fuzzy logic and Genetic Algorithms);     

      ·         Advanced Control Systems for drug delivery (Adaptive, Predictive, Multivariable and Sliding Mode).

      Research Unit:  UISPA – System Integration and Process Automation Unit –  Part of the LAETA (Associated Laboratory of Energy, Transports and Aeronautics) a I&D Unit of the Foundation for Science and Technology (FCT), Portugal  - INEGI (

      Principal Researcher at the Clinical Anaesthesia Research Centre of the Centro Hospitalar do Porto, Serviço de Anestesiologia.

    Publicações mais Recentes:

       Catarina S. Nunes has more than 100 Journal Publications in peer review International Journals; several books and book chapters;  more than 20 Conference Proceedings Papers; and many conference communications . Only a selection is presented here

      Leitão Ferreira, A., Nunes, C, J. Mendes and P. Amorim (2018). "Transition to Loss of Consciousness during Anesthesia Induction with Remifentanil and Propofol: EEG Patterns." Journal of Neurosurgical Anesthesiology 30(4): 396-397

       Pinho, S., F. Lagarto, B. Gomes, L. Costa, C.S. Nunes and C, Oliveira (2018). “Escore CR-POSSUM e Índice de Apgar Cirúrgico como fatores preditivos para a alocacão de pacientes após cirurgia colorretal.” Revista Brasileira de Anestesiologia 68 (4): 351-357.

      A. L. Ferreira, J. Mendes, P. Amorim and C. S. Nunes, "EEG signatures at the transition between conscious and unconscious state during induction of general anesthesia with remifentanil and propofol," 2018 IEEE International Symposium on Medical Measurements and Applications (MeMeA), Rome, 2018, pp. 1-5 (ISBN: 978-1-5386-3392-2).

      A. L. Ferreira, J. Mendes, P. Amorim and C. S. Nunes, "Neuro-fuzzy models to predict the required propofol amount for loss of consciousness during general anesthesia: a preliminary study," 2018 IEEE International Symposium on Medical Measurements and Applications (MeMeA), Rome, 2018, pp. 1-5 (ISBN: 978-1-5386-3392-2). 

       Machado, H.S., C. Nunes, A. Marques, I. Almeida, A. J. Barros, E. Castro Alves, A. Sousa Pereira, J. Barros and P. Barbosa (2018). "Ten Years of Activity at a Portuguese University Hospital Emergency Department: A Retrospective Observational Study" General Medicine (Los Angeles) 6(1): 309. 

       Costa, I.C., C. S. Nunes and H. S. Machado (2018). "Mode of Delivery and Labour Analgesia: A Study of Preference in Portuguese Pregnant Women." Journal of Anesthesia & Clinical Research 9(8): 849. 

       Pereira, C., D. Sobreira Fernandes, A. Carmezim Mota, G. Gonçalves, S. Pinho, M. Araújo, F. Pereira, A. Saraiva, M. Paiva, C.S. Nunes, C. Cavaleiro and H. Machado (2018). “Anaesthesia - Related Fears - A Cross - Sectional Survey Among the Portuguese Population.” International Journal of Anesthesiology & Research 6(1): 494-499.

      C. S. Nunes “Didática da estatística em educação a distância e eLearning”, in eLearning no Ensino Superior, 1st ed, J. António Moreira e Cristina Pereira Vieira, EdS. Coimbra, Portugal: CINEP/IPC, 2017, pp. 61-76 (ISBN: 978-989-99463-4-7

       Araújo, A.M., J. Guimarães, C. S. Nunes, P.S. Couto, E. Amadeu (2017). “Post-operative pain after 
      ultrasound transversus abdominis plane block versus trocar site infiltration inlaparoscopic nephrectomy: a
       prospective study.” Revista Brasileira de Anestesiologia 67 (5): 487-492.

      Castro, A., F. G. de Almeida, P. Amorim and C. S. Nunes (2017). "A novel multivariate STeady-state index 
      during general ANesthesia (STAN)." Journal of Clinical Monitoring and Computing 31 (4): 851-860. 

        Ferreira, A., S. Vide, R. Correia, C. Nunes and P. Amorim (2017). "Predicting Loss of Consciousness Using
       the Pupillary Light Reflex." Journal of Neurosurgical Anesthesiology 29(4): 555-556.

      Nunes, C., A. Leitao Ferreira, R. Correia and P. Amorim (2017). "Towards Personalized Anesthesia: Predictive Factors for Propofol Requirements for Loss of Consciousness." Journal of Neurosurgical Anesthesiology 29(4): 563-564.

        Vide, S., R. Correia, T. Cabral, P. Antunes, J. Teixeira, C. Nunes and P. Amorim (2017). "Intrapatient Variability of the Pupillary Pain Index to Remifentanil." Journal of Neurosurgical Anesthesiology 29(4): 527.


      Guimaraes, J., D. Pinho, C. S. Nunes, C. S. Cavaleiro and H. S. Machado (2016). "Effect of Boussignac continuous positive airway pressure ventilation on PaO2 and PaO2/FIO2 ratio immediately after extubation in morbidly obese patients undergoing bariatric surqery: a randomized controlled trial." Journal of Clinical Anesthesia 34 (November): 562-570.

      P. Dias, D. Caeiro, L. Aires, D. Moreira, F. Goulão, S. Henriques, J.A. Moreira, and C.S. Nunes “eLearning no Ensino Superior Português: perspetivas de líderes académicos e pedagógicos”, in Práticas e Cenários de Inovação em Educação Online, 1st ed, P. Dias, D. Moreira e A. Quintas-Mendes, EdS. Lisboa, Portugal: Universidade Aberta, 2016, pp. 11-45 (ISBN: 978-972-674-786-4

      A.L. Ferreira, C.S. Nunes, J. Gabriel, and P. Amorim, “The influence of two different drug infusion profiles on the pharmacodynamics model performance,” in World Congress on Medical Physics and Biomedical Engineering, June 7-12, 2015, Toronto, Canada, IFMBE Proceedings, Vol 51, David A. Jaffray, Eds, USA: Springer International Publishing, 2015, Part VII, pp. 874-880 (ISBN: 978-3-319-19386-1)

      2015      P. Dias, D. Caeiro, L. Aires, D. Moreira, F. Goulão, S. Henriques, A. Moreira, C. Nunes, “Educação a Distância e ELearning no Ensino Superior”.  Lisboa, Portugal: Universidade Aberta (ISBN: 978-972-674-769-7  )

      Araujo AM, Santos F, Guimaraes J, Nunes CS, Casal M (2015). "Living-donor Kidney Transplantation: Predictive Factors and Impact on Post-transplant Outcome." Transplantation Proceedings 47(4): 938-941

      Guimaraes J, Araujo AM, Santos F, Nunes CS, Casal M (2015). "Living-donor and Deceased-donor Renal Transplantation: Differences in Early Outcome-A Single-center Experience." Transplantation Proceedings 47(4): 958-962

      Santos F, Guimaraes J, Araujo AM, Nunes CS, Casal M (2015). "Deceased-donor Kidney Transplantation: Predictive Factors and Impact on Postoperative Outcome." Transplantation Proceedings 47(4): 933-937

      Ribeiro PO, Antunes LM, Nunes CS, Silva HB, Cunha RA, Tome AR (2015). "The Effects of Different Concentrations of the alpha(2)-Adrenoceptor Agonist Medetomidine on Basal Excitatory Synaptic Transmission and Synaptic Plasticity in Hippocampal Slices of Adult Mice." Anesthesia and Analgesia 120(5): 1130-1137

      A. Castro, P. Amorim, C.S. Nunes, and F. Gomes de Almeida, “Effect of propofol and remifentanil on a somatosensory evoked potential indicator of pain perception intensity in volunteers,” Journal of Clinical Monitoring and Computing, 29(5): 561-567, 2015

        S. Brás, A. Georgakis, L. Ribeiro, D.A. Ferreira, A. Silva, L. Antunes, and C.S. Nunes, “Electroencephalogram-based indices applied to dogs" depth of anaesthesia monitoring,” Research in Veterinay Science, vol. 97(3), pp. 597–604, 2014.

        H.S. Machado, C.S. Nunes, P. Sá, A. Couceiro, A. Moreira da Silva, and A. Águas, “Increased lung inflammation with oxygen supplementation in tracheotomized spontaneously breathing rabbits: an experimental prospective randomized study,” BMC Anesthesiology, vol. 4, number 86, 1 October 2014.

      S. Brás, S. Gouveia, L. Ribeiro, D.A. Ferreira, L. Antunes, and C.S. Nunes, "Fuzzy logic model to describe anesthetic effect and muscular influence on EEG Cerebral State Index," Research in Veterinary Sciencey, vol. 94(3), pp. 735–742, 2013.

      C.S. Nunes, F. Lobo, and P. Amorim, "ARX modeling of drug effects on brain signalsduring general anesthesia", in 21st Mediterranean Conference on Control & Automation (MED) Platanias-Chania, Crete, Greece, IEEE, 2013, pp. 202-205 (ISBN: 978-1-4799-0995-7)

      S. Brás, D.A. Ferreira, L. Antunes, L. Ribeiro, C. S. Nunes, and S. Gouveia, "EMG contributes to improve Cerebral State Index modeling in dogs anesthesia", in 2011 33rd ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY NY, USA: IEEE, 2011, pp. 6593-6596 (ISBN: 978-1-4244-4121-1).

       D. Ferreira, C. Nunes, L. Antunes, and P. Amorim, "Propofol and Remifentanil: Contributions to the Improvement of Target Controlled Infusion and BIS Monitoring," in Advances in Medicine and Biology, Volume 2, L. V. Berhardt, Ed. New York, USA: Nova Science Publishers, Inc, 2010, pp. 57-92 (ISBN: 978-1-60876-288-0).

      C.S. Nunes, T. Mendonça, J. Lemos, and P. Amorim, "Feedforward adaptive control of the Bispectral Index of the EEG using the intravenous anaesthetic drug propofol," International Journal of Adaptive Control and Signal Processing, vol. 23 (5), pp. 485-503, 2009.

      C.S. Nunes, D. Ferreira, L. Antunes, F. Lobo, I. Santos, and P. Amorim, "Individual Effect-Site Concentrations of Propofol at Return of Consciousness are Related to the Concentrations at Loss of Consciousness and Age in Neurosurgical Patients," Journal of Clinical Anesthesia, vol. 21 (1), pp. 3-8, 2009.

      Mahfouf, J. Backory, M. Abbod, C.S. Nunes, and D. Linkens, "Monitoring and control of unconsciousness during clinical surgery: Auditory evoked potentials (AEP) versus the clinical gold standard (CGS)," International Journal of Adaptive Control and Signal Processing, vol. 23 (5), pp. 522-540, 2009.

      T. Mendonça, C.S. Nunes, and P. Lago, "Intelligent Control Systems in Anaesthesia," in Intelligent and Adaptive Systems in Medicine, O. C. L. Haas and K. J. Burnham, Eds. New-York, NY, USA: Taylor & Francis Ltd 2008, pp. 53-94 (ISBN: 9780750309943).

    Informações Complementares:

      Fellow of the: Royal Statistical Society; Higher Education Academy.

      Member of the:  Portuguese Statistical Society;  Institute of Electrical & Electronic Engineers (IEEE); the Intitution of Engineering and Technology (IET); IEEE Engineering in Medicine and Biology Society; the International Anesthesia Research Society (IARS); Portuguese Automatic Control Association.

      Affiliate Member of the: European Society of Anaesthesiology (ESA); American Society of Anesthesiologists (ASA).

      Reviewer for the following journals: Acta Médica Portuguesa; Journal of Neurosurgical Anesthesiology; Medical Engineering and Physics; IEEE Transactions on Automation Science and Engineering; Anesthesiology; IEEE Transactions on Biomedical Engineering; International Journal of Adaptive Control and Signal Processing; Artificial Intelligence in Medicine; Automatica; Engineering Applications of Artificial Intelligence.

      Reviewer for the following conferences:  Annual Conference of the  IEEE Engineering in Medicine and Biology Society; European Control Conference,  Annual Conference of the Portuguese Society of Automatic Control.